Showing posts with label San Francisco. Show all posts
Showing posts with label San Francisco. Show all posts

Sunday, January 15, 2023

Be sure to wear some flowers in your hair

A gray rain fell without ceasing on the 41st Annual JP Morgan Healthcare Conference.  People huddled in hotel doorways and waited on Ubers. The bellman offered me a plastic sleeve for my umbrella as I shook it out. “Water and marble don’t go well together,” he said. In San Francisco, we didn’t get the heavy flooding and evacuations seen in SoCal, but our phones lit up with alerts of a dangerous and life-threatening situation.

Security was heavy at the Westin St. Francis. I hadn’t picked up my badge yet, so a blazered guy with an earpiece pointed me to the side entrance, where I navigated another three security people before making it to the roped-off “presenting company check-in” section. My QR code wouldn’t scan, but the friendly young woman in a white silk top said she trusted me. She handed over my badge and lanyard and a bone-white canvas tote bag with a blue embroidered JP Morgan logo. The bag was of a heft and quality that assumed there was a decent chance that its recipient would own a matching sailboat.  

The corridors and stairways of the Westin teemed with characters who in one way or another were looking to make their fortunes in pharmaceuticals.  Tall, bearded banker bros; C-suite executives in dark suits and European eyeglasses; female buy-side analysts with blonde hair yanked straight back who looked like they spent their pre-dawn hours astride a Peloton; South Asian PhD/MBAs. The Colonial Room was SRO, so I leaned against the back wall and listened to our CEO talk about how we are transforming the practice of medicine and how our operating margin was on track to reach 32% by 2025.

I spent most of my week down the hill at the Omni, shuttling between conference rooms. The company I work for is Large Cap (nestled between between Mega Cap and Medium Cap), and as such my days were stacked with one-hour blocks of presentations from different small-to-medium biotechs looking to “partner” with us. Between two and ten people would show up for each meeting, their eagerness for partnering generally in direct proportion to the number of people there.  

In general, each of these folks was either a Science Person or a Money Person. The Science People wore clothing suggesting a teenager being dragged to a wedding. Many had one minor but unignorable physical characteristic: a wandering eye, excessive ear hair, dermatitis. The Money People clustered at both ends of the fashion spectrum, either wearing suits, or going for venture capitalist casual chic: fleece vest or quarter-zip sweater over a checked button-down shirt and high-end running shoes. On’s were in abundance. Despite being Money People, they were not necessarily slick: I observed one BD woman inspect her split ends assiduously through our entire meeting.

As they spoke to us of novel therapeutic targets and cytokines and mouse models, I would regret that I had selected English as my undergraduate major. 

“Never drive a fancy car,” a former boss once said to me, “Because we don’t want to give the impression that we are profiting off of the ill health of the American public.” I suppose it’s tempting to look at all this cynically and to disapprove of the baser desires behind it. The industry has done plenty of unsavory stuff over the years. My favorite communist podcasters would go a step further and call out the unsustainability of the entire system: look no further, they might argue, than the contrast between the bright lights, fancy presentations, and carbon footprint over at the Westin St. Francis, and the rising flood waters outside.    

I can’t argue with any of that. I also know that I’m not in a position to work for free, and I suspect you aren’t either. And despite my attempts at clever commentary above, the people I spent time last week with were not caricatures; they were intelligent people trying to do decent work. Meanwhile, people are still getting sick and dying from nasty diseases.  If, God forbid, one of our kids were to come down with one of these diseases, we would pray for someone to show up with some medicine. We can all dream of a day when our elected representatives prioritize medical research over DDG 51 Burke-class Aegis Destroyers. But in the meantime, the powerful and greedy pharmaceutical industry is our best hope. Wish them luck.    

Tuesday, May 29, 2018

Machina ex machina



Last week, I sat in a room in San Francisco with 40 of my colleagues for four days, listening to business school professors and start-up founders talk about Disruption and Transformation.  One presenter talked about how all of the innovation – as measured in companies with a market cap of $1 billion or more – is coming out of the US and China, and that Europe has been left way behind, presumably because the Europeans worry too much about the welfare of their citizens and not enough about their start-ups.  We visited a start-up incubator where young ambitious CS majors pitched us on their ideas to solve the problem of the “data abyss.”   We talked about how Wal-Mart – the largest private employer on the planet – is investing heavily in automation and AI, and that many of the 1.5 million people who work for Wal-Mart could be out of a job soon.*   

Outside, homeless people drifted around Market Street like zombies.  A leathery-skinned black man approached me on Monday as I was walking up to Chinatown and laughed as he punched himself in the jaw repeatedly.  Thursday I saw another man with a scraggly beard, prone on the sidewalk in front of the Nordstoms and flailing violently every few seconds, while a policeman and an EMT stood by, not quite sure how to approach him.  My colleagues reported encounters with people copulating on street corners and defecating in alleyways.

The weekend before, I took my daughters to Panera for dinner one night (highly recommend the blood orange lemonade, BTW).  Panera has always pretty operationally efficient as far as I could tell: the workflows are well organized and they give you the flashing tile thing that buzzes when your order is up so you can find a place to sit down in the meantime.  Now they’ve taken things up a notch and installed touch-screen ordering monitors, which are placed in offensive-line formation in front of the regular counter, which is at this point still manned by a human being.  Evidently, this is part of “Panera 2.0,” and the business press has unsurprisingly talked about this as a cost-saving measure and that people will lose jobs, all of which is true.  Perhaps more frightening is that most people would prefer interacting with yet another screen to having even fleeting, transactional contact with another human being.  But this shouldn’t surprise anyone at this point.

On the flight home, I read an article in the Guardian about how the Church of England has taught Amazon’s Alexa to recite the Lord’s Prayer.